Seth's riding in the PMC again this year, donate!
Please check out his site. There are numerous links on the left-side navigation about his participation in the PMC in the past and his passion for this cause.
Update: I forgot to mention Seth is also considering doing a ride for MS, because a local radio DJ is offering to promote his PMC effort on the radio if he raises $500 for the MS ride. If you'd prefer to give to MS, let Seth know so he can determine whether or not to do it.